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When prescribing TMP/SMX to children,the primary care NP should recall that:


A) dosing is based on the trimethoprim component of the drug.
B) TMP/SMX should not be prescribed for children younger than 2 years.
C) folic acid supplements must be given to children who take this medication.
D) the medication should be given three or four times per day because of rapid metabolism.

E) A) and B)
F) A) and D)

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The primary care NP teaches a patient about TMP/SMX before prescribing it to treat a urinary tract infection (UTI) .Which statement by the patient indicates a need for further teaching?


A) "I will take this medication with food."
B) "I should drink a full glass of water with each dose."
C) "I should stay out of direct sunlight and use sunscreen."
D) "I should report any ringing in my ears or a sore throat."

E) A) and B)
F) All of the above

Correct Answer

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A patient is seen in the clinic with a 1-week history of frequent watery stools.The primary care NP learns that a family member had gastroenteritis a week prior.The patient was treated for a UTI with a sulfonamide antibiotic 2 months prior.The NP should suspect:


A) Clostridium difficile-associated disease (CDAD) .
B) viral gastroenteritis.
C) serum sickness reaction.
D) recurrence of the UTI.

E) B) and D)
F) All of the above

Correct Answer

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A patient has been taking trimethoprim-sulfamethoxazole (TMP/SMX) for 14 days.The patient calls the primary care nurse practitioner (NP) to report fever,rash,and enlarged lymph nodes.The NP should suspect:


A) serum sickness reaction.
B) immediate sensitivity reaction.
C) cytotoxic hypersensitivity reaction.
D) cell-mediated hypersensitivity reaction.

E) A) and D)
F) B) and C)

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A

An 80-year-old patient who has COPD takes TMP/SMX for acute exacerbations,which occur three or four times each year.To monitor this patient for adverse drug reactions,the primary care NP should order:


A) liver function tests.
B) blood urea nitrogen and creatinine.
C) serum bilirubin levels.
D) a complete blood count (CBC) with differential.

E) B) and C)
F) None of the above

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D

A patient is taking sulfisoxazole.The patient calls the primary care NP to report abdominal pain,nausea,and insomnia.The NP should:


A) change to TMP/SMX.
B) tell the patient to stop taking the drug immediately.
C) reassure the patient that these are minor adverse effects of this drug.
D) order a CBC with differential, platelets, and a stool culture.

E) A) and D)
F) None of the above

Correct Answer

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A primary care NP prescribes TMP/SMX for a patient who is experiencing an exacerbation of COPD.The patient calls the NP 2 days later to report increased fever,cough,and shortness of breath.The NP should tell the patient:


A) to stop taking the medication.
B) that symptoms such as sore throat and arthralgia are more worrisome.
C) to continue the medication because these are signs of the disease process.
D) that sulfisoxazole (Gantrisin) will be prescribed instead to minimize side effects.

E) All of the above
F) B) and C)

Correct Answer

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A

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